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Best Antibiotic for Sinus Infection – The choice of antibiotic for sinus infection depends on various factors, including the severity of the infection, the suspected or identified causative agent, and individual patient factors. Commonly prescribed antibiotics for sinus infections include amoxicillin, amoxicillin/clavulanate (Augmentin), doxycycline, and trimethoprim/sulfamethoxazole (Bactrim). However, it’s crucial to consult with a healthcare professional, such as a doctor or pharmacist, who can assess your specific situation, consider any allergies or contraindications, and provide appropriate antibiotic treatment based on your needs.